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Generic Leukeran (Chlorambucil)
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Leukeran
Leukeran is a medication used to treat several kinds of cancer and other conditions.
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Leukeran - not very

About About Drugs. Manufacturer Back to Top. Side Effects of Cancer Treatment. A recent study has shown Chlorambucil to be detoxified by human glutathione transferase Pi GST Pan enzyme that is often Leukegan over-expressed in cancer tissues. Leukeran is used to treat several types of cancer, including Lwukeran disease and certain types of leukemia or lymphoma. To this end, he made analogues that were less electrophilic by exchanging the sulphur with a nitrogen, leading to the nitrogen mustards. Fathers to be: What to pack for hospital. Leukeran Usage Back to Top. Before receiving Leukeran, tell your doctor about all of your medical conditions including if you have:. Leukeran is classified as an "alkylating agent. Take them at least an hour before food or 3 hours after eating. Mouthy ulceration. Keep this and all medications out of the reach of children. Women who are pregnant should tell their doctors before they begin taking this drug. How you have it Chlorambucil is a tablet. Chlorambucil pronounced as klor am' bue sil. Talk to your doctor about your specific risk. Childhood Cancer Genomics. Cancer Causes and Prevention. Patients who have demonstrated hypersensitivity to chlorambucil should not be given the drug. Reporting side effects Data sources Disclaimer What it is used for Treatment of Hodgkin's disease, certain forms of non-Hodgkin's lymphomachronic lymphocytic leukaemiaWaldenstrom's macroglobulinaemia, advanced ovarian adenocarcinoma. Chlorambucil's current use is mainly in chronic lymphocytic leukemia, as it is well tolerated by most patients, though chlorambucil has been largely replaced by fludarabine as first-line treatment in younger patients. Use extra care to prevent bleeding while shaving or brushing your teeth. Other drugs may interact with chlorambucil, including prescription and over-the-counter medicines, vitaminsand herbal products. You can read more about the scheduling of medicines as well as the different scheduling categories on our Scheduling of medicines and poisons information page. Late Effects of Childhood Cancer Treatment. All rights reserved. Talk to your doctor about your specific risk. New York: Pergamon. Monthly newsletter. Leukeran Chlorambucil Tablets, 2-mg, 1 tablet. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. What is the medicines and poisons schedule? Email Address. This medicine is available from a pharmacist and requires a prescription. Contact your health care provider immediatelyday or night, if you should experience any of the following symptoms:. Chlorambucil was approved Leuksran medical use in the United States in Please check Leukeran try again Please enter recipient's email Leukeraj email is invalid. Unless your doctor tells you otherwise, continue your normal diet. All medicines and poisons in Australia are categorised by how they are made available to the public. Download leaflet Reporting side effects Data sources Disclaimer What it is used for Treatment of Hodgkin's disease, certain forms of non-Hodgkin's lymphomachronic lymphocytic leukaemiaWaldenstrom's macroglobulinaemia, advanced ovarian adenocarcinoma. Funding Strategy. Breastfeeding warning: It is not known if this drug passes into breast milk. Why is this medication prescribed? Read our privacy policy. For general information or questions, call If your levels are too low, your doctor will reduce your dosage. This medication comes in tablet form Leuketan is usually taken once daily for 3 to 6 weeks. Do not stop taking Leukeran or change the dose without first checking with your doctor. This depends on many factors such as your weight and your response to the treatment. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Some may be better suited for you than others. Not every pharmacy stocks this drug. Wash soiled clothing and linens separately from other laundry. Integrative Therapies Editorial Board. Keep all appointments with the laboratory. This drug can also cause liver damage. Chlorambucil Leukeran interact with other medications. It is important to take your medicine regularly and at the same time each day Ask your doctor or pharmacist if you are not sure of the instructions on the bottle label. Leukeran Cautionary Labels Back to Top. Pharmacologic Class: Alkylating agent. This includes vitamins, herbal supplements and over the counter remedies. Leukeran is the brand name for generic chlorambucil. Questions to Ask About Cancer. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Chlorambucil is used treat a certain type of chronic lymphocytic leukemia CLL; a type of cancer of the white blood cells. Always Lrukeran the label. We'll collect your pet's prescription information at Checkout. The Gumberg Family Resource Center provides educational Leukeram for patients and caregivers. This information is not intended Leuieran be used as a substitute for professional Leikeran advice, diagnosis, or Leukkeran. Ask for information on sperm or egg banking. Be sure to include periods of rest between energy-draining activities. Get emergency medical help if you have signs of an allergic reaction: hives ; difficulty breathing; swelling of your face, lips, tongue, or throat. Starts with Contains. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Tell your doctor if you miss a menstrual period. Live vaccines include measles, mumps, rubella MMRrotavirus, typhoid, yellow fever, varicella chickenpoxzoster shinglesand nasal flu influenza vaccine. Clinical Trials Research. Chlorambucil may cause side effects. The scheduling of chemotherapy is set based on the type of cells, rate at which they divide, and the time at which a given drug is likely to be effective. Other side effects not listed above may also occur in some people. Tell your doctor if any of these symptoms are severe or do not go away: nausea vomiting sores in the mouth and throat tiredness missed menstrual periods in girls and women Some side effects can be serious. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

Apologise: Leukeran

Leukeran Menosan
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Leukeran Vitria
It is important not to become pregnant or father a child Lejkeran you're having treatment and for a few months afterwards. Leukerqn your levels are too low, your doctor will reduce your dosage. Leukeran Images. What Leukeran is used for Leukeran Lekueran chlorambucil as the active ingredient. Do not take Leukeran if you are pregnant or breast feeding unless you and your doctor have discussed the risks and benefits involved. Recent Public Laws. Contact your veterinarian immediately if you see any of these signs. This may cause inflammation in different parts of the body which can cause serious side effects. All medicines can have side effects. Fever Effects on the nerves are called peripheral neuropathy. Chlorambucil belongs to a group of drugs called alkylating agents. When to Call the Doctor Fever of Chlorambucil is a chemotherapy medication. Use effective birth control to prevent pregnancy during treatment.
Common use

Leukeran is a medication used to treat several kinds of cancer and other conditions including Hodgkin's disease (a type of lymphoma), malignant lymphoma (including lymphosarcoma), clasmocytoma, chronic lymphocytic leukemia, giant follicular lymphoma, hairy cell leukemia (a sub-type of chronic lymphoid leukemia), myeloma, ovarian cancer, breast cancer, Waldenstr?m macroglobulinemia (lymphoplasmacytic lymphoma), Letterer-Siwe disease (genetically stipulated proliferation of histiocytes), chorionepithelioma of the uterus, glomerular nephritis, Beh?et disease (a form of vasculitis), dermatomyositis, rheumatoid arthritis, sarcoidosis, uveitis, nephrotic syndrome. Leukeran's active substance is chlorambucil, a bifunctional alkylating agent.



Dosage and direction

Take exactly as prescribed by your doctor. Follow all instructions. The recommended initial dosage for short course of treatment is 0.1 to 0.2 mg/kg body weight (4-10 mg for an average patient) taken daily during 3-6 weeks. The daily dose may be taken as a single dose. In case of the sudden fall in th white blood count or bad tolerance by the patient the dosage should be carefully adjusted. Supporting course of treatment is administered individually.



Precautions

Carefulness should be exercised in the patients with inhibited bone marrow function (expressed as leukopenia, thrombocytopenia, and anemia, including ones associated with a malignant process and on the background of the previous radiotherapy or chemotherapy), severe liver disease and kidney failure, acute gastrointestinal disease, in pregnant and breastfeeding women. Blood cell count,leukocytes count, platelets count, and Hb examination should be performed at least once weekly.



Contraindications

Leukeran cannot be used in the patients with hypersensitivity to its components (including other alkylating agents).



Possible side effect

The most common side effects are nausea, vomiting, changes in menstrual period. Contact your doctor immediately if you have following adverse reactions: painful or difficult urination, fever, chills, black, tarry or bloody stools, easy bruising or bleeding, blood in urine, swollen extremities, sores in mouth or on lips, small red spots on the skin, jaundice, cough, lower back or side pain, joint pain, abdominal pain, confusion, hallucinations, muscle twitching, agitation, trouble walking, weakness, paralysis.



Drug interaction

Inform your doctor about all prescribed and over-the-counter medications, herbal products and food supplements you use.



Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. Skip the missed dose if it is almost time of your next dose. Do not try to compensate a missed dose by taking an extra one.



Overdose

If you suspect overdose inform your doctor immediately about it and seek immediate medical attention. Signs of overdose are agitation, seizures, loss of balance or coordination.



Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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